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. 2015 Jan 8;9(1):e3443.
doi: 10.1371/journal.pntd.0003443. eCollection 2015 Jan.

Buruli ulcer in South Western Nigeria: a retrospective cohort study of patients treated in Benin

Estelle Marion  1 , Kevin Carolan  2 , Ambroise Adeye  3 , Marie Kempf  4 , Annick Chauty  3 , Laurent Marsollier  5
Affiliations

Buruli ulcer in South Western Nigeria: a retrospective cohort study of patients treated in Benin

Estelle Marion et al. PLoS Negl Trop Dis. .

Abstract

Nigeria is known to be endemic to Buruli ulcer, but epidemiological data are remarkably rare. Here, we present a large cohort of 127 PCR-confirmed M. ulcerans infection patients coming from Nigeria and treated in a neighbouring country, Benin. Severe lesions and delay of consultation are factors that should encourage establishment of a treatment centre in South Western Nigeria.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Localisation of Buruli ulcer patients in Nigeria.
(A) Nigerian districts where Buruli ulcer patients were already described at least once, and neighbouring countries areas where Buruli ulcer is endemic. The number of cases described since 1967 is indicated for each Nigerian district. (B) Location of Benin and Nigerian patients coming in CDTUB-Pobè for treatment of Buruli ulcer.
Figure 2
Figure 2. Buruli ulcer Nigerian patients.
(A) Number of new Buruli ulcer patients coming from Nigeria and treated in Buruli ulcer treatment centre of Pobè, Benin between 2005 and 2013. (B) Age of patients by gender, *** P = 0.0001. (C) Distribution of patient consultation delay.
Figure 3
Figure 3. A typical category III lesion of Buruli ulcer.
Most Nigerian patients presented in medical center of Pobè in Benin with extensive ulcerative lesions. On the picture, the lesion of a Nigerian 10 years old child on the right thigh and with the typical characteristic of a late stage of the disease: large painless ulceration with presence of necrosis and undermined edges.
See this image and copyright information in PMC

References

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