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Meta-Analysis
. 2015 Jan 8;5(1):e005997.
doi: 10.1136/bmjopen-2014-005997.

Methadone maintenance treatment programme reduces criminal activity and improves social well-being of drug users in China: a systematic review and meta-analysis

Hua-Min Sun  1 , Xiao-Yan Li  1 , Eric P F Chow  2 , Tong Li  1 , Yun Xian  1 , Yi-Hua Lu  1 , Tian Tian  1 , Xun Zhuang  1 , Lei Zhang  3
Affiliations
Meta-Analysis

Methadone maintenance treatment programme reduces criminal activity and improves social well-being of drug users in China: a systematic review and meta-analysis

Hua-Min Sun et al. BMJ Open. .

Abstract

Objective: Methadone maintenance treatment (MMT) has been implemented in China since 2004 and has expanded into a nationwide programme. This study aims to evaluate changes in social functioning, family relations and drug-related criminal behaviour among MMT clients in China.

Design: Systematic review and meta-analysis.

Methods: Both English and Chinese literature databases, including PubMed, Chongqing VIP Chinese Science and Technology Journals Database (CQVIP), China National Knowledge Infrastructure (CNKI) and Wanfang Data, were comprehensively searched over the period 2004-2014 for studied indicators. Study selection, quality assessment and data extraction were conducted according to the PRISMA (preferred reporting items for systematic reviews and meta-analyses) Statement. Meta-analyses were conducted using Comprehensive Meta-Analysis Biostat software.

Results: Thirty-eight articles were included in this review (1 in English and 37 in Chinese). The self-reported arrest rate decreased from 13.1% (95% CI 9.1% to 18.5%) at baseline to 3.4% (95% CI 1.5% to 7.7%) and 4.3% (95% CI 1.6% to 11.4%) after 6 and 12 months of MMT intervention, respectively. The rate of drug selling decreased from 7.6% (95% CI 3.8% to 14.8%) at baseline to 1.9% (95% CI 0.6% to 6.2%) and 3.0% (95% CI 1.0% to 8.9%) after 6 and 12 months of intervention, respectively. Similarly, the rates of selling sex for drugs and drug-related crime decreased from 5.3% (95% CI 2.4% to 11.1%) and 9.9% (95% CI 6.8% to 14.2%) at baseline to 1.1% (95% CI 0.5% to 2.3%) and 3.4% (95% CI 2.5% to 4.5%) at 6 months, then to 0.8% (95% CI 0.3% to 1.9%) and 3.4% (95% CI 0.8% to 13.1%) at 12 months after treatment initiation, respectively. In contrast, the rate of employment of clients and the proportion of clients having a good relationship with their family increased substantially from 26.4% (95% CI 22.9% to 30.1%) and 37.9% (95% CI 32.0% to 44.2%) to 41.6% (95% CI 36.6% to 48.0%) and 59.6% (95% CI 48.1% to 70.2%) at 6 months, then to 59.8% (95% CI 52.4% to 66.8%) and 75.0% (95% CI 69.0% to 80.2%) at 12 months after treatment initiation, respectively.

Conclusions: MMT has significantly reduced criminal activity, and improved employment rate and social well-being, of clients of the MMT programme. MMT is an effective measure to help drug users to resume societal and familial functions in China.

Keywords: PUBLIC HEALTH.

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Figures

Figure 1
Figure 1
Flow chart for selection of studies. CNKI, China National Knowledge Infrastructure; CQVIP, Chongqing VIP Chinese Science and Technology Journals Database; MMT, methadone maintenance treatment.
Figure 2
Figure 2
Changes in criminal activity, social well-being and family relations in Chinese clients at various intervention periods before and after initiation of methadone maintenance treatment (MMT): (A) rate of arrest by police; (B) rate of drug selling; (C) rate of selling sex for drugs; (D) rate of drug-related crime; (E) employment rate; (F) proportion having good relationship with family; (G) proportion having contact with former drug-user friends on a daily basis.
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See this image and copyright information in PMC

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