Association of various risk factors with prognosis and hospitalization cost in Chinese patients with acute myocardial infarction: A clinical analysis of 627 cases

Abstract

Acute myocardial infarction (AMI) is the leading cause of morbidity and mortality in the developed world and is becoming increasingly more common in developing countries. The risk factors affecting the prognosis of Chinese patients may differ from those in other populations. This study was conducted to investigate the potential risk factors that may correlate with prognosis and hospitalization costs of Chinese AMI patients. A total of 627 hospitalized AMI patients were recruited and their general information and relevant laboratory parameters were collected. Accordingly, the patients were grouped into different subgroups and potential risk factors and their correlations with prognosis and hospitalization costs were analyzed. Age, high blood pressure, infarct location and percutaneous coronary intervention (PCI) were the variables significantly associated with the differences in the prognosis of AMI patients (P<0.05), whereas times and duration of hospitalization, high blood pressure, infarct location and PCI treatment were found to be significantly associated with the cost of hospitalization (P<0.05). However, the AMI patients enrolled in this study may not be representative of all AMI patients in China. In addition, the prognosis of these patients was limited to their hospital stay. Therefore, long-term follow-up requires careful assessment.

Keywords: Chinese population; acute myocardial infarction; hospitalization cost; prognosis; risk factors.

Figure 1

The prognosis of acute myocardial infarction patients was shown to be significantly correlated with age, hypertension prevalence and the number of patients undergoing percutaneous coronary intervention (PCI) treatment.

Figure 2

Single-factor analysis of relevant factors in different prognostic groups. The prognosis of acute myocardial infarction (AMI) patients was positively correlated with percutaneous coronary intervention (PCI) treatment and negatively with age distribution and incidence of hypertension (P<0.05). The proportion of AMIs located in the inferior and anterior wall predominated in both the death and non-death groups. Infarct location: A, anterior wall; B anteroseptal; C inferior wall; D posterior wall; E right ventricle; F high lateral wall; G multiple-wall.

Figure 3

Single-factor analysis of correlation between hospitalization cost and risk factors. The statistical analysis demonstrated that times and duration of hospitalization (P=0.045 and P<0.0001, respectively), high blood pressure (P=0.029), infarct location (P=0.046) and number of patients udergoing percutaneous coronary intervention (P<0.0001) were significantly associated with hospitalization cost. Infarct location: A, anterior wall; B, anteroseptal; C inferior wall; D, posterior wall; E, right ventricle; F high lateral wall; G multiple-wall.