Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 May;35(5):1016-27.
doi: 10.1097/IAE.0000000000000418.

Fundus changes in branch retinal vein occlusion

Sohan Singh Hayreh  1 , M Bridget Zimmerman
Affiliations

Fundus changes in branch retinal vein occlusion

Sohan Singh Hayreh et al. Retina. 2015 May.

Abstract

Purpose: To investigate systematically the retinal changes in branch retinal vein occlusion (BRVO) and their natural history.

Methods: The study comprised 214 consecutive patients with BRVO (144 major BRVO and 72 macular BRVO eyes) seen within 3 months of onset. Ophthalmic evaluation at initial and follow-up visits included recording visual acuity, visual fields, and detailed anterior segment and fundus examinations and fluorescein fundus angiography.

Results: Initially, retinal hemorrhages were moderate to severe in the perifovea and macula in at least 65% in major and 52% in macular BRVO; at the fovea, it was 51% in major and 36% in macular BRVO. Initially, macular edema was more marked in major BRVO than in macular BRVO (P = 0.007). Major BRVO had a significantly higher rate of development of serous macular detachment (P = 0.002), epiretinal membrane (P = 0.008), serous retinal detachment (P = 0.002), perivenous sheathing (P < 0.0001), optic disk pallor (P < 0.0001), and lipid deposit (P < 0.0001) compared with macular BRVO. Retinal and disk neovascularization was seen only in major BRVO. The time to resolution of BRVO was significantly longer for major BRVO compared with macular BRVO (P = 0.0002).

Conclusion: Major and macular BRVOs are two distinct clinical entities. Initial and final fundus findings in the two types differ markedly.

PubMed Disclaimer

Conflict of interest statement

Authors have no financial interest or conflict.

Figures

Fig. 1
Fig. 1
Fundus photograph of right eye with superior temporal major BRVO.
Fig. 2
Fig. 2
Fundus photograph of right eye with macular BRVO.
Fig. 3
Fig. 3
Kaplan-Meier curves for the resolution of retinal hemorrhage in different part of the retina in major BRVO.
Fig. 4
Fig. 4
Kaplan-Meier curves for the resolution of retinal hemorrhage in different part of the retina in macular BRVO.
Fig. 5
Fig. 5
Kaplan-Meier curves for the resolution of major and macular BRVO.
See this image and copyright information in PMC

References

    1. Oeller J. Atlas der Ophtlzaimoscopie Wiesbaden. C. Tabs XIII. :1896–1899.
    1. Orth DH, Patz A. Retinal branch vein occlusion. Surv Ophthalmol. 1978;22:357–76. - PubMed
    1. Jaulim A, Ahmed B, Khanam T, Chatziralli IP. Branch retinal vein occlusion: epidemiology, pathogenesis, risk factors, clinical features, diagnosis, and complications. An update of the literature. Retina. 2013;33:901–10. - PubMed
    1. Rogers SL, McIntosh RL, Lim L, et al. Natural history of branch retinal vein occlusion: An evidence-based systematic. Ophthalmology. 2010;117:1094–1101. - PubMed
    1. Gutman FA, Zegarra H. Macular edema secondary to occlusion of the retinal veins. Surv Ophthalmol. 1984;28(Suppl):462–70. - PubMed