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Case Reports
. 2015 Jan 8;2015(1):rju144.
doi: 10.1093/jscr/rju144.

A case series of two glomus tumors of the gastrointestinal tract

Sean Bennett  1 , Mindy Lam  2 , Jason Wasserman  3 , David Carver  4 , Navaaz Saloojee  2 , Terence Moyana  3 , Rebecca A Auer  4 , John Lorimer  4
Affiliations
Case Reports

A case series of two glomus tumors of the gastrointestinal tract

Sean Bennett et al. J Surg Case Rep. .

Abstract

Two recent cases of glomus tumors (GTs) of the gastrointestinal tract presented with symptoms of GI bleeding. GTs, typically benign lesions of mesenchymal origin, are rarely seen in the GI tract, and most commonly involve the distal appendages. This case series discusses the tumor biology, presentation, imaging, endoscopic findings, pathology and management of GTs. While diagnosis of GTs is typically made on final surgical pathology, there are defining characteristics that can separate a GT from a gastrointestinal stromal tumor on endoscopic ultrasound (EUS) and CT imaging. The classic pathological findings are discussed, and surgical decision-making is reviewed. New developments in the form of EUS-guided biopsy and endoscopic submucosal dissection present new avenues for diagnosis and treatment of submucosal lesions of the GI tract, including GTs. While typically a benign tumor requiring no adjuvant therapy, this study discusses some very rare cases of metastatic GT in the literature.

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Figures

Figure 1:
Figure 1:
Endoscopic findings of gastric GT.
Figure 2:
Figure 2:
CT imaging of gastric GT.
Figure 3:
Figure 3:
Gastric GT. Note the well-circumscribed submucosal lesion surrounding small vessels (H&E stain, ×20).
Figure 4:
Figure 4:
Gastric GT. Note central round or oval nuclei with clear, eosinophilic cytoplasm (H&E stain, ×200).
See this image and copyright information in PMC

References

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