Orofacial granulomatosis as a presenting feature of Crohn's disease
- PMID: 25576503
- PMCID: PMC4289786
- DOI: 10.1136/bcr-2013-203005
Orofacial granulomatosis as a presenting feature of Crohn's disease
Abstract
An 11-year-old girl was referred to oral medicine with persistent facial swelling. She was diagnosed with orofacial granulomatosis (OFG) and was treated conservatively for 7 years, with no evidence of systemic illness. Aged 17 she re-presented with a flare up of her OFG, watery diarrhoea and fluctuating febrile episodes. Inflammatory markers were raised and an MR enterogram revealed terminal ileal Crohn's disease. This case highlights that OFG may precede the onset of intestinal Crohn's disease.
2015 BMJ Publishing Group Ltd.
Similar articles
-
Orofacial granulomatosis and erythema multiforme in an adolescent with Crohn's disease.Pediatr Dermatol. 2018 Sep;35(5):e294-e297. doi: 10.1111/pde.13548. Epub 2018 Jun 26. Pediatr Dermatol. 2018. PMID: 30024055
-
Orofacial granulomatosis in children: think about Crohn's disease.Dig Liver Dis. 2015 Apr;47(4):338-41. doi: 10.1016/j.dld.2014.12.012. Epub 2014 Dec 30. Dig Liver Dis. 2015. PMID: 25618553
-
The role of exclusive enteral nutrition in the management of orofacial granulomatosis in children.World J Pediatr. 2016 Nov;12(4):421-424. doi: 10.1007/s12519-016-0045-7. Epub 2016 Nov 3. World J Pediatr. 2016. PMID: 27457793
-
Oral Crohn's disease: is it a separable disease from orofacial granulomatosis? A review.J Crohns Colitis. 2012 Mar;6(2):135-42. doi: 10.1016/j.crohns.2011.07.001. Epub 2011 Aug 9. J Crohns Colitis. 2012. PMID: 22325167 Review.
-
Orofacial granulomatosis--a 20-year review.Oral Dis. 2009 Jan;15(1):46-51. doi: 10.1111/j.1601-0825.2008.01500.x. Oral Dis. 2009. PMID: 19076470 Review.
Cited by
-
Gastrointestinal diseases and their oro-dental manifestations: Part 1: Crohn's disease.Br Dent J. 2016 Dec 16;221(12):794-799. doi: 10.1038/sj.bdj.2016.954. Br Dent J. 2016. PMID: 27982000 Review.
References
-
- Kauzman A, Quesnel-Mercier A, Lalonde B et al. . Orofacial granulomatosis: 2 case reports and literature review. J Can Dent Assoc 2006;72:325–9. - PubMed
-
- Johani A, Moles DR, Hodgson TA et al. . Orofacial granulomatosis: clinical features and long-term outcome of therapy. J Am Acad Dermatol 2010;62:611–20. - PubMed
-
- Saalman R, Mattsson U, Jonell M. Orofacial granulomatosis in childhood—a clinical entity that may indicate Crohn's disease as well as food allergy. Acta Paediatr 2009;98:1162–7. - PubMed
-
- Tilakaratne WM, Freysdottir J, Fortune F. Orofacial granulomatosis: review on aetiology and pathogenesis. J Oral Pathol Med 2008;37:191–5. - PubMed
-
- Leao JC, Hodgson T, Scully C et al. . Review article: orofacial granulomatosis. Aliment Pharmacol Ther 2004;20:1019–27. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical