Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Dec;4(4):382-90.
doi: 10.1007/s13142-014-0278-8.

Five population-based interventions for smoking cessation: a MOST trial

D Fraser  1 , K Kobinsky  1 , S S Smith  1 , J Kramer  1 , W E Theobald  1 , T B Baker  1
Affiliations

Five population-based interventions for smoking cessation: a MOST trial

D Fraser et al. Transl Behav Med. 2014 Dec.

Abstract

Little is known about the relative, additive, and interactive effects of different population-based treatments for smoking cessation. The goal of this study was to evaluate the main and interactive effects of five different smoking interventions. Using the multiphase optimization strategy (MOST), 1,034 smokers who entered a Web site for smokers (smokefree.gov) were randomly assigned to the "on" and "off" conditions of five smoking cessation interventions: the National Cancer Institute's (NCI) Web site (www.smokefree.gov vs a "lite" Web site), telephone quitline counseling (vs none), a smoking cessation brochure (vs a lite brochure), motivational e-mail messages (vs none), and mini-lozenge nicotine replacement therapy (NRT vs none). Analyses showed that the NCI Web site and NRT both increased abstinence; however, the former increased abstinence significantly only when it was not used with the e-mail messaging intervention (messaging decreased Web site use). The other interventions showed little evidence of effectiveness. There was evidence that mailed nicotine mini-lozenges and the NCI Web site (www.smokefree.gov) provide benefit as population-based smoking interventions.

Keywords: MOST research; Nicotine replacement; Smoking cessation; Telephone quitline; Web site evaluation.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Recruitment flow charta
See this image and copyright information in PMC

References

    1. World Health Organization . WHO global report: mortality attributable to tobacco. Geneva, Switzerland: WHO Press; 2012.
    1. Fiore MC, Jaen CR, Baker TB, et al. Treating tobacco use and dependence: 2008 update. Rockville, MD: U.S. Department of Health and Human Services, U.S. Public Health Service; 2008.
    1. Fiore MC, Baker TB. Treating smokers in the health care setting. N Engl J Med. 2011;365(13):1222–1231. doi: 10.1056/NEJMcp1101512. - DOI - PMC - PubMed
    1. Aveyard P, Begh R, Parsons A, et al. Brief opportunistic smoking cessation interventions: a systematic review and meta-analysis to compare advice to quit and offer of assistance. Addiction. 2012;107(6):1066–1073. doi: 10.1111/j.1360-0443.2011.03770.x. - DOI - PubMed
    1. Gollust SE, Schroeder SA, Warner KE. Helping smokers quit: understanding the barriers to utilization of smoking cessation services. Milbank Q. 2008;86(4):601–627. doi: 10.1111/j.1468-0009.2008.00536.x. - DOI - PMC - PubMed