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. 2014 Sep 1:3:6-13.
doi: 10.1016/j.cois.2014.07.004.

The mosquito microbiota influences vector competence for human pathogens

Nathan J Dennison  1 , Natapong Jupatanakul  1 , George Dimopoulos  1
Affiliations

The mosquito microbiota influences vector competence for human pathogens

Nathan J Dennison et al. Curr Opin Insect Sci. .

Abstract

The midgut of insect vectors of human disease contains not only pathogens harmful to human health, but also a diverse microbiota. This microbiota can influence insects' susceptibility to human pathogens, and the capacity to transmit them, through different mechanisms. Understanding the interaction between the vector, its microbiota and transmitted pathogens will provide novel opportunities to limit disease transmission.

Keywords: Aedes; Anopheles; Mosquito; Plasmodium; dengue; innate immunity; microbiota.

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References

    1. Ohkuma M. Termite symbiotic systems: efficient bio-recycling of lignocellulose. Appl. Microbiol. Biotechnol. 2003;61:1–9. - PubMed
    1. Brune A. Termite guts: the world's smallest bioreactors. Trends in Biotechnology. 1998;16:16–21.
    1. Dillon RJ, Dillon VM. The gut bacteria of insects: nonpathogenic interactions. Annu. Rev. Entomol. 2004;49:71–92. - PubMed
    1. Charroux B, Royet J. Drosophila immune response: From systemic antimicrobial peptide production in fat body cells to local defense in the intestinal tract. Fly (Austin) 2010;4:40–47. - PubMed
    1. Ryu J-H, Kim S-H, Lee H-Y, Bai JY, Nam Y-D, Bae J-W, Lee DG, Shin SC, Ha E-M, Lee W-J. Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila. Science. 2008;319:777–782. - PubMed

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