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. 2015 Feb;11(2):67-8.
doi: 10.1038/nrneph.2014.248. Epub 2015 Jan 13.

Glomerular disease in 2014: advances in basic science and translational medicine

Fernando C Fervenza  1 , Sanjeev Sethi  2
Affiliations

Glomerular disease in 2014: advances in basic science and translational medicine

Fernando C Fervenza et al. Nat Rev Nephrol. 2015 Feb.

Abstract

Knowledge of the pathogenesis of glomerular disease and approaches to therapy continued to advance in 2014. Key studies identified thrombospondin type-1 domain-containing protein 7A as an antigenic target in primary membranous nephropathy, and demonstrated efficacy of rituximab as maintenance therapy in relapsing or steroid-dependent nephrotic syndrome and antineutrophil cytoplasmic antibody-associated vasculitis.

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