Vascular-promoting therapy reduced tumor growth and progression by improving chemotherapy efficacy
- PMID: 25584889
- DOI: 10.1016/j.ccell.2014.12.009
Vascular-promoting therapy reduced tumor growth and progression by improving chemotherapy efficacy
Abstract
In this issue of Cancer Cell, Wong and colleagues describe a novel approach of increasing the number of functional blood vessels in tumors using a low-dose therapy regimen of Cilengtide and Verapamil. This method enhanced gemcitabine delivery, uptake, and metabolism within tumor cells to reduce tumor growth and progression.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread.Cancer Cell. 2015 Jan 12;27(1):123-37. doi: 10.1016/j.ccell.2014.10.015. Cancer Cell. 2015. PMID: 25584895
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