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. 2014 Dec;44(4):319-24.
doi: 10.1007/s11084-014-9392-3. Epub 2015 Jan 14.

Molecular crowding and early evolution

Ranajay Saha  1 , Andrew Pohorille, Irene A Chen
Affiliations

Molecular crowding and early evolution

Ranajay Saha et al. Orig Life Evol Biosph. 2014 Dec.

Abstract

The environment of protocells might have been crowded with small molecules and functional and non-specific polymers. In addition to altering conformational equilibria, affecting reaction rates and changing the structure and activity of water, crowding might have enhanced the capabilities of protocells for evolutionary innovation through the creation of extended neutral networks in the fitness landscape.

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References

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