Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2015 Jul;26(7):1478-80.
doi: 10.1681/ASN.2014121161. Epub 2015 Jan 13.

Epigenetic Changes Induced by Hypoxia-Inducible Factor: a Long Way Still To Go as a Target for Therapy?

Masaomi Nangaku  1 , Reiko Inagi  2 , Imari Mimura  3 , Tetsuhiro Tanaka  4
Affiliations
Editorial

Epigenetic Changes Induced by Hypoxia-Inducible Factor: a Long Way Still To Go as a Target for Therapy?

Masaomi Nangaku et al. J Am Soc Nephrol. 2015 Jul.
No abstract available

Keywords: AKI; HIF; acute renal failure; chronic kidney disease; hypoxia; microRNA.

PubMed Disclaimer

Comment on

References

    1. Bhatt K, Wei Q, Pabla N, Dong G, Mi Q-S, Mei C, Dong Z: MicroRNA-687 induced by HIF-1 targets PTEN in renal ischemia-reperfusion injury. J Am Soc Nephrol 26: 1588–1596, 2015 - PMC - PubMed
    1. Tanaka T, Nangaku M: Angiogenesis and hypoxia in the kidney. Nat Rev Nephrol 9: 211–222, 2013 - PubMed
    1. Nangaku M: Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure. J Am Soc Nephrol 17: 17–25, 2006 - PubMed
    1. Rosenberger C, Mandriota S, Jürgensen JS, Wiesener MS, Hörstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU: Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 13: 1721–1732, 2002 - PubMed
    1. Schley G, Klanke B, Schödel J, Kröning S, Türkoglu G, Beyer A, Hagos Y, Amann K, Burckhardt BC, Burzlaff N, Eckardt KU, Willam C: Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues. Am J Pathol 181: 1595–1606, 2012 - PubMed

MeSH terms