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. 2014:2014:239406.
doi: 10.1155/2014/239406. Epub 2014 Dec 22.

Gastroschisis: antenatal sonographic predictors of adverse neonatal outcome

Rachael Page  1 , Zachary Michael Ferraro  1 , Felipe Moretti  1 , Karen Fung Kee Fung  1
Affiliations

Gastroschisis: antenatal sonographic predictors of adverse neonatal outcome

Rachael Page et al. J Pregnancy. 2014.

Abstract

Objectives: The aim of this review was to identify clinically significant ultrasound predictors of adverse neonatal outcome in fetal gastroschisis.

Methods: A quasi-systematic review was conducted in PubMed and Ovid using the key terms "gastroschisis," "predictors," "outcome," and "ultrasound."

Results: A total of 18 papers were included. The most common sonographic predictors were intra-abdominal bowel dilatation (IABD), intrauterine growth restriction (IUGR), and bowel dilatation not otherwise specified (NOS). Three ultrasound markers were consistently found to be statistically insignificant with respect to predicting adverse outcome including abdominal circumference, stomach herniation and dilatation, and extra-abdominal bowel dilatation (EABD).

Conclusions: Gastroschisis is associated with several comorbidities, yet there is much discrepancy in the literature regarding which specific ultrasound markers best predict adverse neonatal outcomes. Future research should include prospective trials with larger sample sizes and use well-defined and consistent definitions of the adverse outcomes investigated with consideration given to IABD.

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Figures

Figure 1
Figure 1
Ultrasound image showing small anterior wall defect beside umbilical cord insertion with small bowel herniation.
Figure 2
Figure 2
Ultrasound image demonstrating intra-abdominal loops of bowel dilatation in fetal gastroschisis at 33 weeks of gestation.
Figure 3
Figure 3
Ultrasound image showing loops of bowel floating free in amniotic fluid in a fetus at 31 weeks of gestation.
Figure 4
Figure 4
3D ultrasound image demonstrating free loops of intestine in amniotic cavity at 34 weeks.
See this image and copyright information in PMC

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