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. 2014 Dec;48(6):409-12.
doi: 10.4132/KoreanJPathol.2014.48.6.409. Epub 2014 Dec 31.

Hybrid granular cell tumor/perineurioma

Sung Sun Kim  1 , Yoo Duk Choi  1 , Jae Hyuk Lee  1 , Chan Choi  1 , Chang Soo Park  1
Affiliations

Hybrid granular cell tumor/perineurioma

Sung Sun Kim et al. Korean J Pathol. 2014 Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1.
Fig. 1.
Right shoulder magnetic resonance imaging reveals a well-circumscribed mass in the right posterior axilla (A). Grossly, it is tan to gray in color (B). At low power, the tumor reveals a whorled and storiform growth pattern (C) and rounded aggregations of granular cells with encircling spindle cells (D). (E) Predominant aggregation of granular cells is also observed. (F) Mature adipose tissue is occasionally admixed with main components of the tumor.
Fig. 2.
Fig. 2.
Immunohistochemical findings of the area in Fig. 1D. Spindle cells are immunopositive for glucose transporter 1 (A, B) and epithelial membrane antigen (C). Granular cells are immunoreactive for S-100 (D, E) and CD68 (F).
Fig. 3.
Fig. 3.
Electron microscopy of the granular cells and perineurial cells derived from formalin-fixed tissue. Granular cells reveal abundant cytoplasm filled with phagolysosomes (A, ×8,000), and spindle cells show irregular basal lamina (arrows) and pinocytic vesicles (arrowheads) (B, ×15,000).
See this image and copyright information in PMC

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