In reply
- PMID: 25589501
- PMCID: PMC4294611
- DOI: 10.1634/theoncologist.2014-0284
In reply
Abstract
Many factors contribute to patient survival in metastatic breast cancer and other late-stage cancers. It is doubtful that adjuvant therapy causes a worse survival outcome. This being said, should resistance develop following adjuvant therapy, the patient needs to be offered a first-line solution that is free of cross-resistance.
Comment in
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Adjuvant Therapy Reduces Rate of Dissemination but Shortens Survival Thereafter.Oncologist. 2015 Jul;20(7):e23. doi: 10.1634/theoncologist.2015-0116. Epub 2015 Jun 11. Oncologist. 2015. PMID: 26069279 Free PMC article.
Comment on
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A pooled analysis of gemcitabine plus docetaxel versus capecitabine plus docetaxel in metastatic breast cancer.Oncologist. 2014 May;19(5):443-52. doi: 10.1634/theoncologist.2013-0428. Epub 2014 Apr 4. Oncologist. 2014. PMID: 24705980 Free PMC article. Clinical Trial.
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Adjuvant therapy-related shortening of survival (ATRESS): an underrated phenomenon.Oncologist. 2015 Jan;20(1):88. doi: 10.1634/theoncologist.2014-0273. Oncologist. 2015. PMID: 25589500 Free PMC article.
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- Palmieri C, Jones A. The 2011 EBCTCG polychemotherapy overview. Lancet. 2012;379:390–392. - PubMed
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- Bonadonna G, Brusamolino E, Valagussa P, et al. Combination chemotherapy as an adjuvant treatment in operable breast cancer. N Engl J Med. 1976;294:405–410. - PubMed
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