Looking into Candida albicans infection, host response, and antifungal strategies
- PMID: 25590793
- PMCID: PMC4601349
- DOI: 10.1080/21505594.2014.1000752
Looking into Candida albicans infection, host response, and antifungal strategies
Abstract
Candida albicans, a commonly encountered fungal pathogen, causes diseases varying from superficial mucosal complaints to life-threatening systemic disorders. Among the virulence traits of C. albicans, yeast-to-hypha transition is most widely acknowledged. Host innate immunity to C. albicans critically requires pattern recognition receptors (PRRs), and defence against C. albicans infection is provided by an exquisite interplay between the innate and adaptive arms of the host immune system.
Keywords: Candida albicans; antifungal; immune response.
References
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- Bai C, Xu XL, Wang HS, Wang YM, Chan FY, Wang Y. Characterization of a hyperactive Cyr1 mutant reveals new regulatory mechanisms for cellular cAMP levels in Candida albicans. Mol Microbiol 2011; 82(4):879-93; PMID:21992526. - PubMed
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