Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989;178(6):337-46.
doi: 10.1007/BF00197452.

Human tumor necrosis factor increases the resistance against Listeria infection in mice

K Kato  1 , A Nakane, T Minagawa, N Kasai, K Yamamoto, N Sato, N Tsuruoka
Affiliations

Human tumor necrosis factor increases the resistance against Listeria infection in mice

K Kato et al. Med Microbiol Immunol. 1989.

Abstract

The resistance in mice against Listeria infection was augmented by treatment with recombinant human tumor necrosis factor (TNF). To elucidate this phenomenon, we examined the effect of TNF on macrophage activation. TNF-treated macrophages had listericidal activity in vitro and superoxide anion production. In addition, macrophage migration was inhibited in the presence of TNF. Therefore, activation of macrophages by TNF was similar to activation by macrophage-activating factor or macrophage-migration-inhibitory factor.

PubMed Disclaimer

References

    1. Infect Immun. 1981 Jul;33(1):11-6 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 Nov;82(22):7626-30 - PubMed
    1. Infect Immun. 1988 Oct;56(10):2563-9 - PubMed
    1. J Exp Med. 1985 Dec 1;162(6):2163-8 - PubMed
    1. Infect Immun. 1980 Jun;28(3):654-9 - PubMed

LinkOut - more resources