Fortification and health: challenges and opportunities
- PMID: 25593151
- PMCID: PMC4288271
- DOI: 10.3945/an.114.007443
Fortification and health: challenges and opportunities
Abstract
Fortification is the process of adding nutrients or non-nutrient bioactive components to edible products (e.g., food, food constituents, or supplements). Fortification can be used to correct or prevent widespread nutrient intake shortfalls and associated deficiencies, to balance the total nutrient profile of a diet, to restore nutrients lost in processing, or to appeal to consumers looking to supplement their diet. Food fortification could be considered as a public health strategy to enhance nutrient intakes of a population. Over the past century, fortification has been effective at reducing the risk of nutrient deficiency diseases such as beriberi, goiter, pellagra, and rickets. However, the world today is very different from when fortification emerged in the 1920s. Although early fortification programs were designed to eliminate deficiency diseases, current fortification programs are based on low dietary intakes rather than a diagnosable condition. Moving forward, we must be diligent in our approach to achieving effective and responsible fortification practices and policies, including responsible marketing of fortified products. Fortification must be applied prudently, its effects monitored diligently, and the public informed effectively about its benefits through consumer education efforts. Clear lines of authority for establishing fortification guidelines should be developed and should take into account changing population demographics, changes in the food supply, and advances in technology. This article is a summary of a symposium presented at the ASN Scientific Sessions and Annual Meeting at Experimental Biology 2014 on current issues involving fortification focusing primarily on the United States and Canada and recommendations for the development of responsible fortification practices to ensure their safety and effectiveness.
Keywords: dietary intake; dietary supplements; folate; folic acid; vitamin B-9.
© 2015 American Society for Nutrition.
Conflict of interest statement
Author disclosures: JT Dwyer is a public trustee of ILSI North America; serves on the scientific advisory boards of ConAgra, Inc., McCormick Spice, the Mushroom Council, the California Walnut Commission, and Bay State Milling; and is a consultant to Nestle, Inc. KL Wiemer and KB Miller are employees of General Mills, Inc. O Dary, MA Philbert, V Tarasuk, and CL Taylor, no conflicts of interest. CL Keen serves on advisory boards of AdvoCare, Herbalife, Mars, Inc., McCormick Spice, and Theralogix. JC King serves on the Scientific Advisory Board for ConAgra; has received research funding from the Almond Board of California, the California Walnut Commission, Thrasher Foundation, Harvest Plus, the Nestle Foundation, USDA, and NIH; and has provided consultation to the Alliance for Potato Research and Education and ILSI North America. PC Gaine and AB Jarvis were employees of ILSI North America when the manuscript was prepared. RL Bailey is a government liaison to the ILSI North America Committee on Fortification.
Similar articles
-
Efficacy of adding folic acid to foods.Int J Vitam Nutr Res. 2012 Jun;82(3):177-86. doi: 10.1024/0300-9831/a000109. Int J Vitam Nutr Res. 2012. PMID: 23258398
-
Chapter 30: historical aspects of the major neurological vitamin deficiency disorders: the water-soluble B vitamins.Handb Clin Neurol. 2010;95:445-76. doi: 10.1016/S0072-9752(08)02130-1. Handb Clin Neurol. 2010. PMID: 19892133 Review.
-
Projected effectiveness of mandatory industrial fortification of wheat flour, milk, and edible oil with multiple micronutrients among Mongolian adults.PLoS One. 2018 Aug 2;13(8):e0201230. doi: 10.1371/journal.pone.0201230. eCollection 2018. PLoS One. 2018. PMID: 30070992 Free PMC article.
-
Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age (Review).Evid Based Child Health. 2013 Jan;8(1):112-201. doi: 10.1002/ebch.1895. Evid Based Child Health. 2013. PMID: 23878126 Review.
-
[Application and significance of fortification in prevention of micronutrient deficiency-induced diseases].Srp Arh Celok Lek. 2006 Oct;134 Suppl 2:139-44. doi: 10.2298/sarh06s2139l. Srp Arh Celok Lek. 2006. PMID: 18172965 Review. Serbian.
Cited by
-
Metagenomic analysis of microbe-mediated vitamin metabolism in the human gut microbiome.BMC Genomics. 2019 Mar 12;20(1):208. doi: 10.1186/s12864-019-5591-7. BMC Genomics. 2019. PMID: 30866812 Free PMC article.
-
Nutritional Description of Processed Foods with Fibre-Related Nutrition Claims in Spain: The BADALI Project.Nutrients. 2023 Aug 20;15(16):3656. doi: 10.3390/nu15163656. Nutrients. 2023. PMID: 37630846 Free PMC article.
-
Precision Nutrition: The Hype Is Exceeding the Science and Evidentiary Standards Needed to Inform Public Health Recommendations for Prevention of Chronic Disease.Annu Rev Nutr. 2023 Aug 21;43:385-407. doi: 10.1146/annurev-nutr-061021-025153. Annu Rev Nutr. 2023. PMID: 37603433 Free PMC article. Review.
-
Connecting the food and agriculture sector to nutrition interventions for improved health outcomes.Food Secur. 2022;14(3):657-675. doi: 10.1007/s12571-022-01262-3. Epub 2022 Feb 1. Food Secur. 2022. PMID: 35126795 Free PMC article. Review.
-
Physicochemical and Sensory Properties and Shelf Life of Block-Type Processed Cheeses Fortified with Date Seeds (Phoenix dactylifera L.) as a Functional Food.Foods. 2023 Feb 3;12(3):679. doi: 10.3390/foods12030679. Foods. 2023. PMID: 36766207 Free PMC article.
References
-
- National Academy of Sciences. Dietary Reference Intakes: guiding principles for nutrition labeling and fortification. Washington: National Academy of Sciences; 2003. - PubMed
-
- Nutritional quality of foods: addition of nutrients, 21 CFR Sect 104 (1980).
-
- Brown KH, Lopez de Romana D, Arsenault JE, Peerson JM, Penny ME. Comparison of the effects of zinc delivered in a fortified food or a liquid supplement on the growth, morbidity, and plasma zinc concentrations of young Peruvian children. Am J Clin Nutr 2007;85:538–47. - PubMed
-
- Dary O. Nutritional interpretation of folic acid interventions. Nutr Rev 2009;67:235–44. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous