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. 2015 Jan;50(1):23-9.
doi: 10.1016/j.jpedsurg.2014.10.024. Epub 2014 Nov 7.

A pain in the NEC: research challenges and opportunities

Gail E Besner  1
Affiliations

A pain in the NEC: research challenges and opportunities

Gail E Besner. J Pediatr Surg. 2015 Jan.

Abstract

This lecture will describe how the properties of heparin-binding EFG-like growth factor (HB-EGF) can be utilized to protect the intestines from necrotizing enterocolitis (NEC), to augment the effects of stem cells in the treatment of NEC, and to improve the production of tissue-engineered intestine. It will also explore the role of the enteric nervous system in the development of NEC.

Keywords: HB-EGF; Intestine; Necrotizing enterocolitis; Tissue engineering.

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