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. 2014;4(4):178-87.
Epub 2014 Dec 10.

Hepatitis B virus infection in patients with blood disorders: a concise review in pediatric study

N Mansouri, A Movafagh, A Sayad, S Ghafouri-Fard, H Darvish, D Zare-Abdollahi, B Emamalizadeh, F Shahvaisizadeh, H Ghaedi, M Bastami, M Kayyal, M Hashemi, Mh Heidari, A Nejatizadeh, M Zamani  1
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Hepatitis B virus infection in patients with blood disorders: a concise review in pediatric study

N Mansouri et al. Iran J Ped Hematol Oncol. 2014.

Abstract

Childhood Hepatitis B virus (HBV) infection causes both medical and public health challenges. Infants who acquire HBV parentally have up to 90% risk of developing chronic HBV infection. It is now estimated that approximately 10% of worldwide cancers are attributable to viral infection, with the vast majority (>85 %) occurring in the developing world. In this distribution, elevated rate and prevalence of HBV marker have been found in patients with malignancies as compared to the general population. By reviewing the web-based search for all Persian and English types of scientific peer review published articles initiated using Iran Medex, MEDLINE/PubMed, CINAHL and other pertinent references on websites about HBV and HCV blood disorders. The high prevalence of HBV and HCV infective markers was detected in patients with different malignancies. Moreover, identification of high prevalence of HBV infective markers in leukemia patients proposed strong association between hepatitis viral infections and leukemia.

Keywords: HBV; HCV; Heterogeneous population; Malignancy; Pediatric.

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Figures

Figure 1
Figure 1
Database selection process
Figure 2
Figure 2
Hepatitis B Virus (HBV), the virus is a spherical particle with a diameter of 42nm (1nm = 0.000000001 metres) and is define as follows. Group: Group VII (ds-RT), Family, Hepadnaviridae, Genus: Orthhepadnavirus, Species: Hepatisis B virus.
Figure 3
Figure 3
Geographic distribution of the prevalence of chronic hepatitis B virus infection [58].
See this image and copyright information in PMC

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