Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jun;20(6):750-9.
doi: 10.1016/j.drudis.2015.01.006. Epub 2015 Jan 17.

Pharmaceutical and biomedical applications of surface engineered carbon nanotubes

Neelesh Kumar Mehra  1 , Keerti Jain  1 , Narendra Kumar Jain  2
Affiliations
Review

Pharmaceutical and biomedical applications of surface engineered carbon nanotubes

Neelesh Kumar Mehra et al. Drug Discov Today. 2015 Jun.

Abstract

Surface engineered carbon nanotubes (CNTs) are attracting recent attention of scientists owing to their vivid biomedical and pharmaceutical applications. The focus of this review is to highlight the important role of surface engineered CNTs in the highly challenging but rewarding area of nanotechnology. The major strength of this review lies in highlighting the exciting applications of CNTs to boost the research efforts, which unfortunately are otherwise scattered in the literature making the reading non-coherent and non-homogeneous.

PubMed Disclaimer

Figures

None
Graphical abstract
Fig. 1
Fig. 1
Various nanocomposites: (a) SWCNTs, (b) MWCNTs, (c) Cup-stacked CNTs, (d) Carbon nanohorns, (e) Fullerenes, (f) Carbon nanotorous, (g) Carbon nanopeapods, and (h) Carbon nanobuds (Adopted from www.google.com; accessed date: 21st September, 2014).
Fig. 2
Fig. 2
(A) Receptor mediated endocytosis targeted drug delivery via parenteral administration of CNTs formulation. (B) CNTs penetrate and cross the plasma cell membrane due to their tiny needle dimension.
Fig. 3
Fig. 3
CNTs conjugates employed in bioactives delivery.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Rastogi V. Carbon nanotubes: an emerging drug carrier for targeting cancer cells. J. Drug Deliv. 2014:1–23. Article ID 670815. - PMC - PubMed
    1. Bartelmess J. Carbon nanomaterials: multi-functional agents for biomedical fluorescence and Raman imaging. Chem. Soc. Rev. 2015 doi: 10.1039/C4CS00306C. (in press) - DOI - PubMed
    1. Smith B.R. Selective uptake of single-walled carbon nanotubes by circulating monocytes for enhanced tumour delivery. Nat. Nanotechnol. 2014;9:481–487. - PMC - PubMed
    1. Gupta R. Fucosylated multiwalled carbon nanotubes for Kupffer cells targeting for the treatment of cytokine-induced liver damage. Pharm. Res. 2013;31:322–334. - PubMed
    1. Brahmachari S. Biotinylated amphiphile-single walled carbon nanotubes conjugate for target-specific delivery to cancer cells. J. Mater. Chem. B. 2014;2:1160–1173. - PubMed