AMPK helps T cells survive nutrient starvation
- PMID: 25607450
- DOI: 10.1016/j.immuni.2014.12.029
AMPK helps T cells survive nutrient starvation
Abstract
Reprogramming of cellular metabolism is crucial for T cells responding to environmental cues. Blagih et al. (2015) reveal that the kinase AMPK directs metabolic adaption of effector T cells upon nutrient limitation and contributes to immune responses in vivo.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo.Immunity. 2015 Jan 20;42(1):41-54. doi: 10.1016/j.immuni.2014.12.030. Epub 2015 Jan 2. Immunity. 2015. PMID: 25607458
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