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Case Reports
. 2015 Jan 6:9:69-71.
doi: 10.2147/OPTH.S69466. eCollection 2015.

Progression to macula-off tractional retinal detachment after a contralateral intraoperative intravitreal bevacizumab injection for proliferative diabetic retinopathy

Leonid Zlotcavitch  1 , Harry W Flynn Jr  2 , Robert L Avery  3 , Aleksandra Rachitskaya  2
Affiliations
Case Reports

Progression to macula-off tractional retinal detachment after a contralateral intraoperative intravitreal bevacizumab injection for proliferative diabetic retinopathy

Leonid Zlotcavitch et al. Clin Ophthalmol. .

Abstract

We report a patient with progression to a macula-off tractional retinal detachment in a fellow eye after a contralateral intraoperative intravitreal bevacizumab injection. A 32-year-old diabetic man noted decreased vision in his left eye 1 week following 25 gauge pars plana vitrectomy, gas tamponade, and intraoperative injection of bevacizumab in his right eye. Left eye visual acuity decreased from 20/80 to 20/200, and macula-off tractional retinal detachment was seen on clinical exam and imaging. Progression of tractional retinal detachment associated with proliferative diabetic retinopathy in a fellow eye after a contralateral intraoperative intravitreal bevacizumab injection may occur.

Keywords: anti-VEGF therapy; diabetes mellitus; fellow eye; tractional retinal detachment.

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Figures

Figure 1
Figure 1
Progression of diabetic tractional retinal detachment, by fundus photography and optical coherence tomography (OCT) of the left eye after a unilateral, right eye intraoperative intravitreal bevacizumab injection. Notes: Fundus photograph (A) and OCT (B) of the left eye before right eye intraoperative intravitreal bevacizumab injection, showing vitreoretinal adhesions and attached macula. Fundus photograph (C) and OCT (D) of the left eye after right eye intraoperative intravitreal bevacizumab injection, showing decreased perfusion of the neovascular tissue and progression of tractional retinal detachment.
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