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Review
. 2015 Jan 8:8:9-17.
doi: 10.2147/TACG.S59024. eCollection 2015.

The genetics of Ménière's disease

Giuseppe Chiarella  1 , C Petrolo  1 , E Cassandro  2
Affiliations
Review

The genetics of Ménière's disease

Giuseppe Chiarella et al. Appl Clin Genet. .

Abstract

Our understanding of the genetic basis of Ménière's disease (MD) is still limited. Although the familial clustering and the geographical and racial differences in incidence strongly suggest a certain role for genetic factors in the development of MD, no convincing evidence for an association with any gene exists, at present. In this review, starting from rational bases for a genetic approach to MD, we explored the numerous reports published in literature and summarize the recent advances in understanding of the genetic fundaments of the disease.

Keywords: Mènière’s disease; etiology; gene; pathogenesis; vertigo.

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