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Case Reports
. 2012 Dec;44(3):176-8.
doi: 10.5152/eajm.2012.41.

A rare thymoma type presenting as a giant intrathoracic tumor: lipofibroadenoma

Yener Aydin  1 , Sare Sipal  2 , Mine Celik  3 , Omer Araz  4 , Ali Bilal Ulas  1 , Fatih Alper  5 , Atila Eroglu  1
Affiliations
Case Reports

A rare thymoma type presenting as a giant intrathoracic tumor: lipofibroadenoma

Yener Aydin et al. Eurasian J Med. 2012 Dec.

Abstract
in English, Turkish

Type B1 thymoma (lipofibroadenoma) is extremely rare. The tumor is characterized by an organoid appearance rich in lymphocytes with medullary differentiation and perivascular spaces. A twenty-three-year-old female patient was admitted to our clinic with complaints of chest pain and dyspnea for six months. Chest computed tomography showed solid and fatty components of masses 21×7 and 5×7 cm with clear borders in the right thoracic cavity. The patient underwent a posterolateral thoracotomy in which the mass, arising from the anterior mediastinum, was resected. Histopathological examination showed that the mass was Type B1 thymoma, and the patient was presented in light of the literature.

Tip B1 timoma (lipofibroadenoma) oldukça nadirdir. Tümör medüller farklılaşma ve perivasküler aralık ile lenfositten zengin organoid bir görünümle karakterizedir. Yirmi üç yaşında bir bayan olgu altı ay önce başlayan göğüs ağrısı ve nefes darlığı şikâyetleri ile kliniğimize başvurdu. Toraks bilgisayarlı tomografide sağ torasik kavitede düzgün kenarlı solid ve yağ dansiteleri içeren bir kitle (21×7, 5×7 cm) görüldü. Olguya uygulanan posterolateral torakotomide anterior mediastenden kaynaklanan bir kitle tespit edilip rezeke edildi. Histopatolojik inceleme Tip B1 timoma olarak bildirilen olgu literatür bilgileri ışığında sunuldu.

Keywords: Lipofibroadenoma; Mediastinum; Thymoma.

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Figures

Figure 1.
Figure 1.
A) Postero-anterior chest radiography shows large mass lesion in right hemithorax. B) Axial contrast-enhanced CT scan shows solid and fatty (white arrow) components of mass. Main vascular structures are compressed by the mass.
Figure 2.
Figure 2.
A) Specimen 21×7.5×7 cm in size was a solid mass with an irregular shape weighing 2180 grams. The cut surface showed that the lesion was solid and fibrotic in appearance and that it had scattered areas of adipose tissue. B) There was no necrosis or hemorrhage. Microscopic examination showed an unusual composite tumor of a conventional type B1 thymoma and a lipofibroadenoma.
See this image and copyright information in PMC

References

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