Ischemia-reperfusion damage
- PMID: 25610264
- PMCID: PMC4261480
- DOI: 10.5152/eajm.2013.24
Ischemia-reperfusion damage
Abstract
Ischemia-reperfusion damage is a complex pathological process that begins with tissue anoxia and continues with the production of free oxygen radicals, expanding with the inflammatory response. The literature suggests the importance of antioxidant and anti-inflammatory treatment to treat ischemia-reperfusion-related tissue damage.
İskemi-reperfüzyon hasarı, dokunun oksijensiz kalması ile başlayan, serbest oksijen radikallerinin üretimi ile devam eden ve inflamatuar yanıtla genişleyen karmaşık patolojik bir süreçtir. Bu literetür bilgileri, iskemi-reperfüzyon doku hasarında antioksidan ve antiinflammatuar tedavinin önemini göstermektedir.
Keywords: Ischemia; reperfusion damage.
References
-
- Semenza GL. Cellular and molecular dissection of reperfusion injury ROS within and without. Circ Res. 2000;86:117–8. - PubMed
-
- Grace PA. Ischaemia-reperfusion injury. Br J Surg. 1994;81:637–47. - PubMed
-
- Li C, Jackson RM. Reactive species mechanisms of cellular hypoxia-reoxygenation injury. Am J Physiol Cell Physiol. 2002;282:C227–41. - PubMed
-
- Parks DA, Williams TK, Beckman JS. Conversion of xanthine dehydrogenase to oxidase in ischemic rat intestine: a reevaluation. Am J Physiol. 1988;254(5 Pt 1):G768–74. - PubMed
-
- Zimmerman BJ, Granger DN. Reperfusion injury. Surg Clin North Am. 1992;72:65–83. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources