Spontaneous and nerve-evoked quantal transmission in regenerated motor terminals
- PMID: 2561465
- DOI: 10.1016/0309-1651(89)90025-8
Spontaneous and nerve-evoked quantal transmission in regenerated motor terminals
Abstract
Quantal acetylcholine release was studied in sciatic nerve-extensor digitorum longus muscle preparations from normal rats and in reinnervated muscles at different times following peroneus nerve crush. The efficiency of nerve-evoked transmission was regained almost completely at a time (20 days after crush) when the secretory response to increased extracellular K+ was very weak. This suggests that K+-induced secretion might be activated through mechanisms at least partially different from those involved in the response to nerve stimulation.
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