[Anti-HBS, anti-CMV, and anti-HIV antibodies and HBS antigen in patients with hemophilia, malignant lymphomas, leukemias and multiple myeloma]

Abstract

In 21 patients with haemophilia, 10 with acute leukaemia, 12 with malignant lymphomas, and 12 with multiple myeloma in whom the risk of viral infection is increased the following antibodies were determined: anti- CMV, anti-HIV, anti-HBs, and HBs antigen by ELISA test. Anti-CMV were found mainly in acute leukaemia (90%), in haemophilia (71.4%), in malignant lymphoma (41.7%) and multiple myeloma (33.3%). In 19% of cases of haemophilia anti-HIV antibodies were present. In other groups these antibodies were not found. In acute leukaemias mostly anti-HBs antibodies were present. The group of haemophiliacs is particularly exposed to infection by these viruses which is connected unquestionably to blood transfusions.