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Case Reports
. 2016 Apr;22(2):374-7.
doi: 10.1177/1078155214568582. Epub 2015 Jan 23.

Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia in pregnancy

Candace B Mainor  1 , Alison P Duffy  2 , Kristin L Atkins  3 , Amy S Kimball  4 , Maria R Baer  4
Affiliations
Case Reports

Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia in pregnancy

Candace B Mainor et al. J Oncol Pharm Pract. 2016 Apr.

Abstract

BCR-ABL inhibitors administered in conjunction with chemotherapy have significantly improved outcomes in Philadelphia chromosome-positive acute lymphoblastic leukemia but, for patients diagnosed during pregnancy, data on risks to the fetus are limited. We report a woman treated with chemotherapy and imatinib mesylate who delivered a healthy baby at 30 weeks, and we discuss available data.

Keywords: Acute lymphoblastic leukemia; imatinib mesylate; pregnancy.

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