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Review
. 2015 Feb;17(2):6.
doi: 10.1007/s11926-014-0480-1.

Giant cell arteritis and polymyalgia rheumatica: an update

Miguel A González-Gay  1 , Trinitario Pina
Affiliations
Review

Giant cell arteritis and polymyalgia rheumatica: an update

Miguel A González-Gay et al. Curr Rheumatol Rep. 2015 Feb.

Abstract

Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two closely related diseases in people aged 50 years and older, which are more frequently observed in Western countries. Despite being common entities, concern still exists about the epidemiology, pathogenesis, and diagnosis of both entities. New imaging techniques, such as 18 fluorodeoxyglucose-positron emission tomography, have proved to be useful in detecting large-vessel involvement in GCA. Corticosteroids are the cornerstone of the therapy in GCA and PMR. Relapses are frequent in these conditions. Unlike methotrexate and tumor necrosis factor-α antagonists, anti-interleukin-6 receptor therapy appears to be useful in patients with GCA and PMR who are refractory to corticosteroids. This review summarizes recent studies on GCA and PMR.

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References

    1. Clin Exp Rheumatol. 2014 May-Jun;32(3 Suppl 82):S79-89 - PubMed
    1. Clin Rheumatol. 2014 Feb;33(2):227-36 - PubMed
    1. Clin Exp Rheumatol. 2012 Jan-Feb;30(1 Suppl 70):S110-3 - PubMed
    1. Clin Exp Rheumatol. 2013 Jan-Feb;31(1):1-7 - PubMed
    1. J Clin Rheumatol. 2012 Jan;18(1):1-7 - PubMed

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