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Review
. 1989 Jul;3(3):363-8.
doi: 10.1007/BF00858547.

Studies of terminal differentiation of electrolyte transport in the renal proximal tubule using short-term primary cultures

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Review

Studies of terminal differentiation of electrolyte transport in the renal proximal tubule using short-term primary cultures

S H Larsson et al. Pediatr Nephrol. 1989 Jul.

Abstract

There are several lines of indirect evidence suggesting that the renal tubule cells have not yet reached terminal differentiation at birth. Methods used in cell biology can now be applied to study renal ontogeny. This review describes how primary cultures of proximal tubule cells from rats can be used to investigate developmental changes in Na permeability and Na-K-ATPase-mediated transport.

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