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. 2015 Mar;4(3):472-80.
doi: 10.1002/cam4.404. Epub 2015 Jan 26.

Cutaneous squamous cell carcinoma in Norway 1963-2011: increasing incidence and stable mortality

Trude E Robsahm  1 , Per Helsing, Marit B Veierød
Affiliations

Cutaneous squamous cell carcinoma in Norway 1963-2011: increasing incidence and stable mortality

Trude E Robsahm et al. Cancer Med. 2015 Mar.

Abstract

The incidence of cutaneous squamous cell carcinoma (SCC) is rapidly increasing in white populations, causing high morbidity and health-care costs. Few studies, however, have described the trends for SCC, as population-based data with a long follow-up are limited. In Norway we have this opportunity and we aimed to describe SCC incidence, mortality and survival rates, according to sex, age, stage, primary anatomical location, and geographical region, for the period 1963-2011, for estimation of future health-care needs. Data were retrieved from the Cancer Registry of Norway. Age-adjusted SCC incidence and mortality rates and 5-year relative survival (in percent) were calculated for 5-year calendar periods. A joinpoint regression model identified the annual percentage change (APC) in rates over the 50-year period. The age-adjusted incidence rate increased ninefold in females and sixfold in males from 1963 to 2011, with APCs of 5.6% (95% confidence interval, CI 4.5, 7.3) and 3.3% (95% CI 1.3, 5.3) in females and males, respectively. SCC incidence rose in all age groups, anatomical locations (except ears in females), and geographical regions, though restricted to localized tumors. Most striking increase was seen in the age group 70-79, in face and head locations and among residents in southern Norway. SCC mortality and survival rates remained relatively stable. Our findings underline an increasing need for SCC treatment in Norway, especially considering the aging population. The findings also call for the creation of particular guidelines for primary prevention of SCC.

Keywords: Cutaneous squamous cell carcinoma; incidence; mortality; population-based; survival.

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Figures

Figure 1
Figure 1
Map of Norway, illustrating the position of the five geographical regions; South, East, West, Middle, and North.
Figure 2
Figure 2
Age-adjusted incidence rates of cutaneous squamous cell carcinoma by geographical region and sex in Norway, 1963–2011.
See this image and copyright information in PMC

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