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. 2015 Jan;6(1):105-6.

doi: 10.1111/jdi.12251. Epub 2015 Jan 1.

Case of aniridia with a heterozygous PAX6 mutation in which the glucagon response to arginine was evaluated

Saeko Osawa¹, Tetsuyuki Yasuda¹, Hideaki Kaneto¹, Naoki Shimo¹, Yuichi Yamamoto¹, Dan Kawamori¹, Takeshi Miyatsuka¹, Taka-Aki Matsuoka¹, Iichiro Shimomura¹

Affiliations

PMID: 25621140
PMCID: PMC4296710
DOI: 10.1111/jdi.12251

Case of aniridia with a heterozygous PAX6 mutation in which the glucagon response to arginine was evaluated

Saeko Osawa et al. J Diabetes Investig. 2015 Jan.

. 2015 Jan;6(1):105-6.

doi: 10.1111/jdi.12251. Epub 2015 Jan 1.

Authors

Saeko Osawa¹, Tetsuyuki Yasuda¹, Hideaki Kaneto¹, Naoki Shimo¹, Yuichi Yamamoto¹, Dan Kawamori¹, Takeshi Miyatsuka¹, Taka-Aki Matsuoka¹, Iichiro Shimomura¹

Affiliation

¹ Department of Metabolic Medicine, Osaka University Graduate School of Medicine Osaka, Japan.

PMID: 25621140
PMCID: PMC4296710
DOI: 10.1111/jdi.12251

No abstract available

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References

1. Yasuda T, Kajimoto Y, Fujitani Y. PAX6 mutation as a genetic factor common to aniridia and glucose intolerance. Diabetes. 2002;51:224–230. - PubMed
1. Bessho M, Murase-Mishiba Y, Tsutsumi C. Glycaemic instability correlates with a hyperglucagonaemic response in patients with type 1 diabetes without residual beta-cell function. Diabetes Res Clin Pract. 2013;102:e38–e40. - PubMed
1. Dames P, Puff R, Weise M. Relative roles of the different Pax6 domains for pancreatic alpha cell development. BMC Dev Biol. 2010;10:39. - PMC - PubMed
1. Lee Y, Wang MY, Du XQ. Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice. Diabetes. 2011;60:391–397. - PMC - PubMed

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