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Review
. 2015 Jan 18;6(1):106-16.
doi: 10.5312/wjo.v6.i1.106.

Hand bone mass in rheumatoid arthritis: A review of the literature

Gamze Kilic  1 , Salih Ozgocmen  1
Affiliations
Review

Hand bone mass in rheumatoid arthritis: A review of the literature

Gamze Kilic et al. World J Orthop. .

Abstract

Rheumatoid arthritis (RA) is a common chronic inflammatory disease and periarticular osteoporosis or osteopenia of the inflamed hand joints is an early feature of RA. Quantitative measurement of hand bone loss may be an outcome measure for the detection of joint destruction and disease progression in early RA. This systematic review examines the published literature reporting hand bone mass in patients with RA, particularly those using the dual X-ray absorptiometry (DXA) methods. The majority of the studies reported that hand bone loss is associated with disease activity, functional status and radiological progression in early RA. Quantitative measurement of hand bone mineral density by DXA may be a useful and practical outcome measure in RA and may be predictive for radiographic progression or functional status in patients with early RA.

Keywords: Dual X-ray absorptiometry; Hand bone density; Osteoporosis; Periarticular; Rheumatoid arthritis.

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Figures

Figure 1
Figure 1
Flow chart. RA: Rheumatoid arthritis; DXA: Dual-X-ray absorptiometry.
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