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. 2015 Feb;9(2):681-684.
doi: 10.3892/ol.2014.2707. Epub 2014 Nov 19.

Oncocytic carcinoma of the salivary gland with thymoma: A case report and review of the literature

Yongcheng Cao  1 , Ming Zhu  2 , Ruiqi Mao  1 , Ruixue Cao  1 , Guoli Yu  1 , Aijun Niu  3
Affiliations

Oncocytic carcinoma of the salivary gland with thymoma: A case report and review of the literature

Yongcheng Cao et al. Oncol Lett. 2015 Feb.

Abstract

Oncocytic carcinoma (OC) arising in the salivary gland is a very rare tumor with only 32 previously reported cases. In this report, we describe a novel case of oncocytic carcinoma with associated thymoma, which arose in the left parotid gland of a 66-year-old male with a history of a painless left parotid mass for 1 year. Oncocytes are large, polygonal cells that are characterized by marked cellular atypia, frequent mitoses, wide eosinophilic granular cytoplasm, a central nucleus and a prominent nucleolus. The follow-up data showed no evidence of recurrence and the patient is in a good health 20 months after the surgery. In the current case, the patient had not only OC but also thymoma, which is exceedingly rare and may represent the first documented case in the literature.

Keywords: PTAH stain; oncocytic carcinoma; salivary; thymoma.

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Figures

Figure 1
Figure 1
The cut surface of the parotid tumor, which was solid.
Figure 2
Figure 2
The tumor of the thymus was encapsulated and its cut surface was and solid.
Figure 3
Figure 3
Oncocytic carcinoma of the parotid gland (stain, hematoxylin and eosin; magnification, ×200).
Figure 4
Figure 4
Mitochondria of the oncocytic carcinoma cells were stained (stain, phosphotungstic acid-hematoxylin; magnification, ×400).
Figure 5
Figure 5
Thymoma, AB type, exhibiting type A with B-like features (stain, hematoxylin and eosin; magnification, ×200).
See this image and copyright information in PMC

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