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. 2014 Dec;4(Suppl 3):S193-8.
doi: 10.4103/2231-0762.149039.

Estimation of salivary β-glucuronidase activity as a marker of periodontal disease: A case control study

Chandra Sekhara Prabhahar  1 , K Thanvir Mohamed Niazi  2 , R Prakash  3 , A Yuvaraj  4 , Somasekhar Goud  5 , P Ravishekar  6
Affiliations

Estimation of salivary β-glucuronidase activity as a marker of periodontal disease: A case control study

Chandra Sekhara Prabhahar et al. J Int Soc Prev Community Dent. 2014 Dec.

Abstract

Aim: The aim of the present study was to estimate the salivary β-glucuronidase level in healthy and diseased periodontium and to correlate the level with clinical measurement.

Materials and methods: 70 patients were included in this study with the age ranging from 30 to 65 years. Both males and females were included. They were divided into two groups: Control having healthy periodontium (n = 20) and experimental having diseased periodontium (n = 50). The parameters recorded were probing pocket depth, probing attachment level, gingival index, β-glucuronidase activity in the saliva, number of white blood cells, neutrophils, lymphocytes count, and platelet count.

Results: It was observed that there was an increase in the level of salivary β-glucuronidase in the experimental subjects than in the control patients, and a significant positive linear relationship existed between salivary β-glucuronidase level and probing pocket depth in the experimental group.

Conclusion: Level of salivary β-glucuronidase increases during inflammation in the periodontium.

Keywords: inflammation; periodontium; saliva; β-glucuronidase.

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Conflict of interest statement

Conflict of Interest: None declared.

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