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Review
. 2014 Oct-Dec;12(4):505-8.
doi: 10.1590/S1679-45082014RC2745. Epub 2014 Nov 18.

Primary hepatic carcinoid tumor: case report and literature review

[Article in English, Portuguese]
Éden Sartor Camargo  1 , Marcelo de Melo Viveiros  1 , Isaac José Felippe Corrêa Neto  1 , Laercio Robles  1 , Marcelo Bruno Rezende  1
Affiliations
Review

Primary hepatic carcinoid tumor: case report and literature review

[Article in English, Portuguese]
Éden Sartor Camargo et al. Einstein (Sao Paulo). 2014 Oct-Dec.

Abstract
in English, Portuguese

Primary hepatic carcinoid tumors are extremely rare neoplasms derived from hormone-producing neuroendocrine cells. It is difficult to make their diagnosis before biopsy, surgical resection or necropsy. A recent publication described only 94 cases of these tumors. There is no sex predilection and apparently it has no association with cirrhosis or preexisting hepatic disease. The most effective treatment is hepatectomy, and resection is determined by size and location of the lesions.

Tumores carcinoides primários do fígado são neoplasias derivadas de células neuroendócrinas produtoras de hormônios, extremamente raras e de difícil diagnóstico antes da biópsia, ressecção cirúrgica ou mesmo da necrópsia. Em recente publicação, descreveram-se apenas 94 casos dessa afecção. É uma doença sem predileção por sexo e que, aparentemente, não tem associação com cirrose, nem com doença hepática preexistente. O tratamento que se demonstra mais eficaz é a hepatectomia, cuja extensão da ressecção é determinada pelo tamanho e pela localização das lesões.

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Figures

Figure 1
Figure 1. (A) Axial computed tomography image - portal phase - middle hepatic vein - contact with lesion. (B) Coronal computed tomography image
Figure 2
Figure 2. Octreotide scintigraphy shows radiomarker uptake in hepatic lesion
Figure 3
Figure 3. Liver with extensive lesion in the right lobe
Figure 4
Figure 4. Histology – epithelioid neoplasm, with medium-sized cells, irregular nuclei, in organoid arrangements and blocks - 8 mitosis per 10 HPF, with necrotic foci
Figura 1
Figura 1. (A) Tomografia computadorizada - corte axial - fase portal - veia hepática media - contato com a lesão. (B) Tomografia computadorizada - corte coronal
Figura 2
Figura 2. Cintilografia com ocreotide - evidenciando captação de radiofarmaco em lesão hepática
Figura 3
Figura 3. Fígado com lesão extensa acometendo lobo hepático direito
Figura 4
Figura 4. Histologia - neoplasia epitelióide com células de tamanho intermediário, nucleos irregulares, dispostas em arranjos organóides e blocos - 8 mitoses por 10 cga com focos de necrose
See this image and copyright information in PMC

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