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. 2015 Jan;40(1):44-55.

Once-Daily, Single-Tablet Regimens For the Treatment of HIV-1 Infection

Once-Daily, Single-Tablet Regimens For the Treatment of HIV-1 Infection

William R Truong et al. P T. 2015 Jan.

Abstract

Once-daily, single-tablet regimens have become integral to the management of human immunodeficiency virus type 1 infection, partly because they may improve adherence due to a lower pill burden. This article reviews the single-tablet options.

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References

    1. Nachega JB, Parienti JJ, Uthman OA, et al. Lower pill burden and once-daily antiretroviral treatment regimens for HIV infection: a meta-analysis of randomized controlled trials. Clin Infect Dis. 2014;58(9):1297–1307. - PMC - PubMed
    1. Hodder SL, Mounzer K, Dejesus E, et al. Patient-reported outcomes in virologically suppressed, HIV-1-infected subjects after switching to a simplified, single-tablet regimen of efavirenz, emtricitabine, and tenofovir DF. AIDS Patient Care STDS. 2010;24(2):87–96. - PubMed
    1. Cohen CJ, Meyers JL, Davis KL. Association between daily anti-retroviral pill burden and treatment adherence, hospitalisation risk, and other healthcare utilisation and costs in a US Medicaid population with HIV. BMJ Open. 2013;3(8):e003028. - PMC - PubMed
    1. Paterson DL, Swindells S, Mohr J, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133(1):21–30. - PubMed
    1. Ickovics JR, Cameron A, Zackin R, et al. Consequences and determinants of adherence to antiretroviral medication: results from adult AIDS clinical trials group protocol 370. Antivir Ther. 2002;7(3):185–193. - PubMed