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Comment
. 2014 Dec 23;18(6):707.
doi: 10.1186/s13054-014-0707-6.

Fluid resuscitation should respect the endothelial glycocalyx layer

Bertrand Guidet, Hafid Ait-Oufella
Comment

Fluid resuscitation should respect the endothelial glycocalyx layer

Bertrand Guidet et al. Crit Care. .

Abstract

Endothelial glycocalyx degradation induced by fluid overload adds to the concern of a detrimental effect of uncontrolled fluid resuscitation and the risk of unnecessary fluid infusion. As a consequence, the use of new tools for monitoring response to fluids appears promising. From that perspective, the monitoring of plasma concentration of glycocalyx degradation markers could be useful.

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