I spy alloreactive T cells
- PMID: 25632032
- DOI: 10.1126/scitranslmed.aaa5083
I spy alloreactive T cells
Abstract
High-throughput sequencing of the T cell receptor Vβ CDR3 region allowed longitudinal tracking of alloreactive T cells in kidney transplant patients, revealing clonal deletion as a mechanism of transplantation tolerance (Morris et al., this issue).
Copyright © 2015, American Association for the Advancement of Science.
Comment on
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Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients.Sci Transl Med. 2015 Jan 28;7(272):272ra10. doi: 10.1126/scitranslmed.3010760. Sci Transl Med. 2015. PMID: 25632034 Free PMC article.
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