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Editorial
. 2015 Feb 24;131(8):689-91.
doi: 10.1161/CIRCULATIONAHA.115.015216. Epub 2015 Jan 28.

Cytoskeleton regulation of ion channels

Affiliations
Editorial

Cytoskeleton regulation of ion channels

Ying Fu et al. Circulation. .
No abstract available

Keywords: Editorials; arrhythmias, cardiac; cytoskeletal proteins; ion channels; protein transport.

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Comment on

  • Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia.
    Smith SA, Sturm AC, Curran J, Kline CF, Little SC, Bonilla IM, Long VP, Makara M, Polina I, Hughes LD, Webb TR, Wei Z, Wright P, Voigt N, Bhakta D, Spoonamore KG, Zhang C, Weiss R, Binkley PF, Janssen PM, Kilic A, Higgins RS, Sun M, Ma J, Dobrev D, Zhang M, Carnes CA, Vatta M, Rasband MN, Hund TJ, Mohler PJ. Smith SA, et al. Circulation. 2015 Feb 24;131(8):695-708. doi: 10.1161/CIRCULATIONAHA.114.013708. Epub 2015 Jan 28. Circulation. 2015. PMID: 25632041 Free PMC article.

References

    1. Ackerman MJ, Mohler PJ. Defining a new paradigm for human arrhythmia syndromes: Phenotypic manifestations of gene mutations in ion channel- and transporter-associated proteins. Circ Res. 2010;107:457–465. - PMC - PubMed
    1. Anderson CL, Delisle BP, Anson BD, Kilby JA, Will ML, Tester DJ, Gong Q, Zhou Z, Ackerman MJ, January CT. Most lqt2 mutations reduce kv11.1 (herg) current by a class 2 (trafficking-deficient) mechanism. Circulation. 2006;113:365–373. - PubMed
    1. Mohler PJ, Rivolta I, Napolitano C, LeMaillet G, Lambert S, Priori SG, Bennett V. Nav1.5 e1053k mutation causing brugada syndrome blocks binding to ankyring and expression of nav1.5 on the surface of cardiomyocytes. Proc Natl Acad Sci U S A. 2004;101:17533–17538. - PMC - PubMed
    1. Furutani M, Trudeau MC, Hagiwara N, Seki A, Gong Q, Zhou Z, Imamura S, Nagashima H, Kasanuki H, Takao A, Momma K, January CT, Robertson GA, Matsuoka R. Novel mechanism associated with an inherited cardiac arrhythmia: Defective protein trafficking by the mutant herg (g601s) potassium channel. Circulation. 1999;99:2290–2294. - PubMed
    1. Asimaki A, Kapoor S, Plovie E, Karin Arndt A, Adams E, Liu Z, James CA, Judge DP, Calkins H, Churko J, Wu JC, MacRae CA, Kleber AG, Saffitz JE. Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy. Sci Transl Med. 2014;6:240ra74. doi: 10.1126/scitranslmed.3008008. - DOI - PMC - PubMed