Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Jan;81(2):157-60.
doi: 10.1007/BF00293893.

Localization of the coagulation factor XIII B subunit gene (F13B) to chromosome bands 1q31-32.1 and restriction fragment length polymorphism at the locus

G C Webb  1 , M Coggan, A Ichinose, P G Board
Affiliations

Localization of the coagulation factor XIII B subunit gene (F13B) to chromosome bands 1q31-32.1 and restriction fragment length polymorphism at the locus

G C Webb et al. Hum Genet. 1989 Jan.

Abstract

In situ hybridization of tritiated cDNA probes for the gene for the B subunit of coagulation factor XIII localized the F13B locus to bands q31-q32.1 on human chromosome 1 and perhaps more precisely to sub-bands 1q31.2 or 1q31.3. Restriction fragment length polymorphisms (RFLPs) were detected with BglII, EcoRI and XbaI. Because the RFLPs detected with each of the three enzymes were concordant in every individual studied and since each showed a similar size difference, it was concluded that the RFLPs probably result from an insertion or deletion of length approximately 0.37-0.4 kb.

PubMed Disclaimer

References

    1. Cold Spring Harb Symp Quant Biol. 1986;51 Pt 1:509-14 - PubMed
    1. J Biol Chem. 1973 Feb 25;248(4):1395-407 - PubMed
    1. Br J Haematol. 1980 Aug;45(4):633-40 - PubMed
    1. Hum Genet. 1986 Dec;74(4):346-52 - PubMed
    1. Cytogenet Cell Genet. 1988;48(1):25-7 - PubMed

LinkOut - more resources