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. 1989 Jan;81(2):183-4.
doi: 10.1007/BF00293899.

Confirmation of linkage disequilibrium between haplotype B (XV-2c, allele 1; KM-19, allele 2) and cystic fibrosis allele in the French population

M Vidaud  1 , A Kitzis, C Ferec, D Bozon, V Dumur, G Giraud, F David, O Pascal, M Auvinet, Y Morel, et al.
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Confirmation of linkage disequilibrium between haplotype B (XV-2c, allele 1; KM-19, allele 2) and cystic fibrosis allele in the French population

M Vidaud et al. Hum Genet. 1989 Jan.

Abstract

In 237 French families with cystic fibrosis (CF) restricted fragment length polymorphisms (RFLPs) were detected by two DNA probes, XV-2c and KM-19, which are tightly linked to the CF allele. As in other European populations linkage disequilibrium is found between the haplotype B (XV-2c, allele 1: KM-19, allele 2) and the CF allele. Linkage disequilibrium alters the probability that a person bearing a given haplotype is a carrier.

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References

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