Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jul 15:89:21-41.
doi: 10.1016/j.addr.2015.01.005. Epub 2015 Jan 26.

Raman imaging of drug delivery systems

Geoffrey P S Smith  1 , Cushla M McGoverin  2 , Sara J Fraser  1 , Keith C Gordon  3
Affiliations
Review

Raman imaging of drug delivery systems

Geoffrey P S Smith et al. Adv Drug Deliv Rev. .

Abstract

This review article includes an introduction to the principals of Raman spectroscopy, an outline of the experimental systems used for Raman imaging and the associated important considerations and limitations of this method. Common spectral analysis methods are briefly described and examples of interesting published studies which utilised Raman imaging of pharmaceutical and biomedical devices are discussed, along with summary tables of the literature at this point in time.

Keywords: Chemometrics; Drug delivery; Drug dissolution; Multivariate methods; Polymeric microparticles; Pre-processing; Raman imaging; Solid dispersions.

PubMed Disclaimer

MeSH terms

Substances