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Comment
. 2015 Feb;17(2):107-9.
doi: 10.1038/ncb3095.

A niche role for periostin and macrophages in glioblastoma

Mario Leonardo Squadrito  1 , Michele De Palma  1
Affiliations
Comment

A niche role for periostin and macrophages in glioblastoma

Mario Leonardo Squadrito et al. Nat Cell Biol. 2015 Feb.

Abstract

Macrophages facilitate tumour progression, but it is unclear whether this capability is influenced by tumour-initiating cells. Glioblastoma stem cells are now shown to secrete periostin, a matrix protein that recruits protumoral macrophages and enhances glioblastoma progression in mice.

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References

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