Control of ciliation in embryogenesis
- PMID: 25633272
- DOI: 10.1038/ncb3103
Control of ciliation in embryogenesis
Abstract
The protrusion of cilia into extracellular space provides cells with sensors of localized environmental cues that include fluid flow, mechanical force and important growth factors such as Hedgehog. Live imaging has now captured the initial appearance of cilia during embryogenesis, and defined lineage-specific determinants that restrict extra-embryonal ciliogenesis.
Comment on
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Lineage specificity of primary cilia in the mouse embryo.Nat Cell Biol. 2015 Feb;17(2):113-22. doi: 10.1038/ncb3091. Epub 2015 Jan 19. Nat Cell Biol. 2015. PMID: 25599390 Free PMC article.
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