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. 1989 Jan;4(1):105-9.
doi: 10.1016/0888-7543(89)90322-4.

A genetic linkage map of five marker loci in and around the Duchenne muscular dystrophy locus

J D Chen  1 , J F Hejtmancik, G Romeo, M Lindlof, C Boehm, C T Caskey, W Kress, K H Fischbeck, M Dreier, S Serravalle, et al.
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A genetic linkage map of five marker loci in and around the Duchenne muscular dystrophy locus

J D Chen et al. Genomics. 1989 Jan.

Abstract

Linkage analysis of five marker loci in and around the Duchenne muscular dystrophy (DMD) locus, DXS84, DXS206, DXS164, DXS270, and DXS28, was conducted with 499 families. Overall, the best multipoint distances were found to be DXS84-3.7 +/- 0.6 cM-DXS206-1.0 +/- 0.4 cM-DXS164-1.9 +/- 0.6 cM-DXS270-12.0 +/- 1.1 cM-DXS28. A comparison of this linkage map with the established physical map suggests the presence of hot spots for recombination in the DMD locus.

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