Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Dec 11;6(3):5596.
doi: 10.4081/pr.2014.5596. eCollection 2014 Aug 12.

A case of Protracted Diarrhea in a Newborn: a Diagnostic Challenge

Catarina Mendes  1 , Catarina Figueiredo  1 , Helena Mansilha  1 , Elisa Proença  2 , Dulce Oliveira  2 , Rosa Lima  3 , Carmen Carvalho  2
Affiliations

A case of Protracted Diarrhea in a Newborn: a Diagnostic Challenge

Catarina Mendes et al. Pediatr Rep. .

Abstract

Congenital diarrhea comprises a broad range of pathologies and often requires a thorough workup and immediate treatment. Although rare, microvillous inclusion disease (MVID) should be included in differential diagnosis of this presentation in the neonate. We report the case of a 36-week newborn who developed signs of severe dehydration and lethargy, requiring fluid resuscitation and total parenteral nutrition. MVID was diagnosed by recognition of profuse secretory diarrhea after an exhaustive etiological investigation, confirmed by DNA analysis.

Keywords: diarrhea; microvillous inclusion disease; protracted.

PubMed Disclaimer

Conflict of interest statement

Conflict of interests: the authors declare no potential conflict of interests.

Similar articles

See all similar articles

Cited by

References

    1. Sherman PM, Mitchell DJ, Cutz E.Neonatal enteropathies: defining the causes of protracted diarrhea of infancy. J Pediatr Gastroenterol Nutr 2004;38:16-26. - PubMed
    1. Berni Canani R, Terrin G, Cardillo G, et al. Congenital diarrheal disorders: improved understanding of gene defects is leading to advances in intestinal physiology and clinical management. J Pediatr Gastroenterol Nutr 2010;50:360-6. - PubMed
    1. Ruemmele FM, Schmitz J, Goulet O.Microvillous inclusion disease (microvillous atrophy). Orphanet J Rare Dis. 2006;1:22. - PMC - PubMed
    1. Cutz E, Rhoads JM, Drumm B, et al. Microvillus inclusion disease: an inherited an inherited defect of brush-border assembly and differentiation. N Engl J Med 1989; 320:646-51. - PubMed
    1. Canani RB, Terrin G.Recent progress in congenital diarrheal disorders. Curr Gastroenterol Rep 2011;13:257-64. - PubMed

LinkOut - more resources