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Comment
. 2015 Feb 17;112(7):1921-2.
doi: 10.1073/pnas.1500077112. Epub 2015 Jan 30.

Chemical proteomics reveals a second family of cyclic-di-AMP hydrolases

John D Helmann  1
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Comment

Chemical proteomics reveals a second family of cyclic-di-AMP hydrolases

John D Helmann. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

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References

    1. Corrigan RM, Gründling A. Cyclic di-AMP: Another second messenger enters the fray. Nat Rev Microbiol. 2013;11(8):513–524. - PubMed
    1. Witte G, Hartung S, Büttner K, Hopfner KP. Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates. Mol Cell. 2008;30(2):167–178. - PubMed
    1. Woodward JJ, Iavarone AT, Portnoy DA. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science. 2010;328(5986):1703–1705. - PMC - PubMed
    1. Rao F, et al. YybT is a signaling protein that contains a cyclic dinucleotide phosphodiesterase domain and a GGDEF domain with ATPase activity. J Biol Chem. 2010;285(1):473–482. - PMC - PubMed
    1. Huynh TN, et al. An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence. Proc Natl Acad Sci USA. 2015;112:E747–E756. - PMC - PubMed

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