Insect-protected event DAS-81419-2 soybean (Glycine max L.) grown in the United States and Brazil is compositionally equivalent to nontransgenic soybean

Abstract

The transgenic soybean event DAS-81419-2 contains genes that encode the Cry1F, Cry1Ac, and PAT proteins. Cry1F and Cry1Ac provide protection against key lepidopteran insect pests, while PAT confers tolerance to the herbicide glufosinate. To satisfy regulatory requirements for the safety evaluation of transgenic crops, studies were conducted in the United States and Brazil to evaluate the nutrient and antinutrient composition of event DAS-81419-2 soybean. On the basis of the results of these studies, event DAS-81419-2 soybean is compositionally equivalent to nontransgenic soybean. This conclusion concurs with numerous other published studies in soybean and other crops where compositional equivalence between the transgenic crop and its nontransgenic comparator has been demonstrated.

Keywords: DAS-81419-2; crop composition; risk assessment; safety evaluation; soybean.

Figure 1

Site means for ADF and NDF in soybean forage. The shaded area represents the literature range and locations are represented by the following symbols: ○ = Richland, IA; × = Atlantic, IA; + = Carlyle, IL; Δ = Wyoming, IL; □ = Frankfort, IN;◇ = Fisk, MO; ● = La Plata, MO; ▲ = York, NE; ■ = Brunswick, NE; ◆ = Germansville, PA; # = Montividiu, Goiás; ∼ = Indianópolis, Minas Geráis. “Isoline” = near-isogenic nontransgenic line. Note that each nontransgenic commercial variety was included, on average, at only half of the field sites in the U.S. study, so the range of data for these entries is expected to be narrower than that of the isoline and DAS-81419-2 entries, which were present at all 10 sites.